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How CBD Oil Works and Its Interaction With the Endocannabinoid System

Oct 7th 2020

How CBD Oil Works and Its Interaction With the Endocannabinoid System

It’s no myth. It’s not magic. It is CBD oil. CBD oil is a hemp oil supplement that contains CBD, also known as cannabidiol. More and more people are taking CBD oil to help with various ailments and finding relief. With such a wide range of possible benefits, it can almost sound too good to be true. So what is really going on? What is the science behind the fast-selling supplement that continues to bring so many people relief?

The Endocannabinoid System

CBD is believed to provide relief because of its interaction with the endocannabinoid system. This system is a branch of the nervous system that was unknown to scientists until the late 20th century.1 The endocannabinoid system has receptor sites at which cannabinoids interact and produce various effects.

There are two types of cannabinoids worth mentioning, endocannabinoids and phytocannabinoids. Endocannabinoids are endogenous, meaning they originate in the body. Phytocannabinoids originate from the cannabis plant. Although phytocannabinoids are not naturally produced in the human body, they interact with the endocannabinoid system at the same receptor sites as endocannabinoids and help to modulate the system’s effect on the body.

The endocannabinoid system isn’t just found in humans. It has been found in nearly all animal life!1 The same way humans find relief, many people have noticed that our furry friends like dogs, cats, and horses find relief from CBD oil as well!

What Can the Endocannabinoid System Do?

Research has shown evidence that the endocannabinoid system modulates the following:

  • Anxiety and stress1
  • Inflammatory conditions1
  • Pain1
  • Metabolism1
  • Neurodegenerative conditions1
  • Pulmonary function1
  • Cardiovascular function1
  • Neuroinflammation (which has strong links to epilepsy)2

Can CBD Do All of This Alone?

CBD, cannabidiol, is only one of the many phytocannabinoids found in cannabis. While many studies have focused primarily on CBD and/or THC, there are plenty of other parts of the cannabis plant that are believed to have therapeutic properties. It has long been hypothesized that an “entourage effect,” a synergistic effect, comes from consuming a cannabis oil that contains a fuller spectrum of the cannabis plant compounds.3 Full-spectrum and broad-spectrum CBD hemp oils contain more phytocannabinoids, terpenes, and flavonoids than CBD isolate, which contains just CBD.

What Does Complete Hemp Offer?

Complete Hemp is here to help! We offer a wide range of product lines, including not only cannabis oils but skincare products as well as pain and skin relief creams with CBD. For CBD hemp oils, Complete Hemp offers CBD isolate, full-spectrum cannabis oil, and two broad-spectrum cannabis oils: 2-1 ratio CBD-CBG, and 1-1 ratio CBD-CBG. There is also CBD oil for dogs, cats, and horses as well!

All of Complete Hemp’s products are:

  • Organic
  • CO2 extracted
  • Paraben-free
  • Non-GMO
  • Gluten-free
  • No preservatives
  • Vegan
  • Made in the USA

Whether you are just beginning your healing journey with CBD oil, or you are a veteran CBD user that is looking to find a better brand than what you have used in the past, Complete Hemp is here for you!


  1. Silver RJ. The Endocannabinoid System of Animals. Animals (Basel). 2019 Sep 16;9(9):686. doi: 10.3390/ani9090686. PMID: 31527410; PMCID: PMC6770351.
  2. Cheung KAK, Peiris H, Wallace G, Holland OJ, Mitchell MD. The Interplay between the Endocannabinoid System, Epilepsy and Cannabinoids. Int J Mol Sci. 2019;20(23):6079. Published 2019 Dec 2. doi:10.3390/ijms20236079
  3. Ben-Shabat S, Fride E, Sheskin T, Tamiri T, Rhee MH, Vogel Z, Bisogno T, De Petrocellis L, Di Marzo V, Mechoulam R. An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity. Eur J Pharmacol. 1998 Jul 17;353(1):23-31. doi: 10.1016/s0014-2999(98)00392-6. PMID: 9721036.